AstraZeneca’s Crestor (rosuvastatin calcium) is a cholesterol-lowering drug, approved for use in adults aged 65 and older and in adults with elevated LDL-cholesterol. It is also used in patients with an elevated risk of heart disease and stroke.

The drug was first approved for use in the US in November 2003. It was first approved in Japan in July 2008.

Crestor is a cholesterol-lowering medication that is used as an adjunct to diet and exercise to lower LDL-cholesterol.

The drug is available by prescription only and has been available in pharmacies since 1999. Crestor is available in 5 mg, 10 mg, 20 mg, and 40 mg doses.

“AstraZeneca has been using Crestor to address many of the challenges of managing high cholesterol and cardiovascular disease in patients,” said Dr. David Nissen, President of the American College of Cardiology. “In patients with heart disease and high LDL-cholesterol, Crestor can help to reduce the risk of heart attack and stroke.”

Crestor, which is sold under the brand name Crestor, is a prescription medication that belongs to a class of drugs called statins.

Crestor is the generic name for Crestor, a brand name drug manufactured by Merck. It contains the same active ingredient, rosuvastatin calcium, as Crestor.

AstraZeneca’s Crestor is a cholesterol-lowering drug, approved for use in adults aged 65 and older and in adults with elevated LDL-cholesterol.

The drug is available in 5 mg, 10 mg, 20 mg, and 40 mg doses. It is indicated for the treatment of patients with an elevated risk of heart disease and high LDL-cholesterol.

The most common side effects of Crestor include weight gain, abdominal pain, and weakness. A patient who is taking the drug may develop symptoms such as fatigue, decreased appetite, dry mouth, and nausea. A patient who takes Crestor may also experience irregular heartbeats, increased heart rate, or palpitations.

The drug is not recommended for use in patients with hypercholesterolemia or high levels of high-density lipoprotein (HDL)-cholesterol. A patient who is taking the drug may also experience symptoms such as vomiting, nausea, and stomach pain.

“Our goal is to provide patients with effective treatment and minimize the risk of side effects,” said Dr. John A. MacDermid, President and CEO of AstraZeneca.

“Crestor is a widely used medication for the treatment of cholesterol levels in patients with elevated risk of cardiovascular disease. Patients should be aware of the potential side effects and the importance of taking the medication exactly as directed.”

Dr. Steven E. Korsmeyer, Professor of Internal Medicine at the Mayo Clinic and the Chief Medical Officer of AstraZeneca, said “Crestor can help lower LDL-cholesterol and prevent heart disease in patients with an elevated risk of cardiovascular disease, such as diabetes and stroke. Patients with these conditions are more at risk of cardiovascular events.”

Patients should seek treatment with Crestor if they are taking any medications that may interact with Crestor. Some common drugs that interact with Crestor include:

• Cimetidine (Tagamet HB) - Tagamet belongs to a class of medications known as the anticoagulants. It works by preventing the clotting of blood. As a result, it lowers the risk of heart attack and stroke.
• Lisinopril (Zestril, Zestril Zestril 20mg, and others) - Zestril is an ACE inhibitor. It lowers blood pressure and is a statin.
• Cholesterol-lowering medications (e.g., lovastatin, simvastatin) - Statins, particularly lovastatin, can decrease HDL-cholesterol and increase LDL-cholesterol. Statins may lower LDL-cholesterol in some patients.
• Lithium - This medication, commonly known as Eskalith, is a cholesterol-lowering medication commonly used to treat some mental health conditions.
• Crestor (rosuvastatin calcium) - Crestor is a prescription drug.

Introduction to Crestor (Rosuvastatin)

Crestor, commonly known by its trade name Rosuvastatin, is a statin medication used to lower cholesterol levels in individuals who have experienced significant cardiovascular diseases, such as heart failure, liver disease, and kidney disease. It belongs to a class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs).

Market Size and Revenue

The global market for statin medication is estimated to reach USD 1.90 billion in 2023[1].

Market Drivers

Several factors are driving the growth of the statin medication market:

• Generic Motives: The growing demand for statins, particularly in inflammatory conditions, is a significant factor[1][3].
• Pharmacy Profit Make-up: The availability of generic statins, such as Crestor, can enhance profit margins, driving patients to purchase and buy cheaper medications[3].
• Health Risks and Side Effects: While the risk of gastrointestinal side effects is relatively common, Crestor has been shown to be generally well-tolerated and manageable[3].
• Quantity Enhancement: GrowingQuantity of prescription statins, such as Crestor, can increase the supply, thereby increasing the market demand for them[3].
• Impact of Insurance: While insurance can cover medications like Crestor, underline is a term that refers to the cost of a specific drug, potentially affecting the appropriateness of using the drug without insurance[3].

Generic vs Prescription Options

Choosing between generic vs. brand-name drugs depends on several factors, including:

• Generic:The cost may vary based on the brand name and manufacturer, but generic Rosuvastatin is the most commonly used medication. Generics are cost-effective, while prescriptionsreetings generically encompass a wide range of drugs[1][3].
• Generic Name: The generic version of the drug is often referred to as Crestor, while the brand name is Rosuvastatin, hence the difference in cost[1][3].
• Advantages: TheGENES benefit, while not as extensively explored, it is an option for individuals requiring statins who cannot afford the brand name versions[3].

Competitive Landscape

The statin market is highly competitive, with several major pharmacy names:

• Lan negotiates with eDrugstore for 90-day supply of Crestor;
• Pfizer Inc.'s Crestor Global is an eDrugstore brandorporates the globalPfizer into theP; and
• AstraZeneca Co. is an eDrugstore brandbranch formed by its subsidiaryA and its subsidiary, Zeneca subsidiary, in order to form a new pharmaceutical companyA[2].

Price Projections

The cost of Crestor can range from $130 for 30 tablets of 60 tablets to $1,200 for 60 tablets of 120 tablets. While generic Rosuvastatin is less expensive due to generic competition, patients can find lower prices for 30 tablets of 60 tablets with brand-name Crestor:

• $0.37 per 30-day supply: Of this amount, $1.08 per 30 tablets is available for 60 tablets refers to a supply cost of $130, while generic Crestor can be more affordable due to generic competition:
• : Of this amount, $1.14 per 30 tablets is available for 60 tablets refers to a supply cost of $130, while generic Crestor can be more affordable:

Patients can also opt for brand-name medications with generic competition: Lan negotiates with eDrugstore for 90-day supply of Crestor; AstraZeneca negotiates with pdrugs for 90-day supply of Crestor; and AstraZeneca contracts with Zen Fascias for 90-day supply of Crestor.

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Crestor Rosuvastatin (5mg) 30 Tablets

This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.

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$12.95

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DescriptionWhat is Crestor Rosuvastatin (5mg)?

• Rosuvastatin is a statin used to lower cholesterol levels in the blood, thereby reducing the risk of cardiovascular events such as heart attack, stroke and liver damage. Rosuvastatin is a lipid-lowering medication primarily used to lower LDL cholesterol levels, a major risk factor for cardiovascular events. It works by reducing the production of bad cholesterol, thereby lowering high-density lipoprotein (a bad cholesterol) levels. Rosuvastatin is thought to work by blocking a specific enzyme in the liver, in arteries, that produces cholesterol. It may also reduce the production of insulin, which is essential for proper blood lipid production.
• Rosuvastatin is also used to treat high blood pressure and hypertension, as well as certain other conditions such as inhibitors of the enzyme beta-cell lipase. Rosuvastatin may also be used for the prevention of certain cancers, such as gastrointestinal (GI) tract (colorectal) cancer.
• Rosuvastatin is also used to lower the risk of strokes, deep vein thrombosis (DVT) and pulmonary embolism (PE).

In recent years, the use of statins, the class of drugs commonly used to treat high blood pressure and cholesterol, has increased. These drugs, in addition to cholesterol-lowering drugs, act to lower cholesterol levels, which is often a result of dietary modifications in the diet. However, statins, such as rosuvastatin (Crestor), have been associated with several adverse outcomes, including heart attack, stroke, liver damage, and cardiovascular events (heart attacks and strokes). Statins, such as rosuvastatin, can cause serious, long-term cardiovascular effects and should be avoided in patients taking statins. Therefore, we investigated the risk of stroke, heart attack, and liver damage associated with statin use in patients with hyperlipidemia.

Rosuvastatin in the Body

Rosuvastatin, a cholesterol-lowering medication, is primarily used to treat patients with coronary heart disease (CHD) and to lower LDL (low-density lipoprotein) levels. It is commonly prescribed to lower cholesterol and triglycerides while still taking rosuvastatin. Rosuvastatin is available in both oral and intravenous formulations, and it is usually taken once a day. The usual starting dose is 2.5 mg daily for 10 weeks. The effects of rosuvastatin on lipid profiles can be seen in a small population of patients with hyperlipidemia. The risk of heart attacks, stroke, and liver damage has been reported to be similar to those seen in patients taking statins alone. These risks of cardiovascular events are higher in patients taking statins as compared with those taking statins alone.

Rosuvastatin has been found to be more effective than statins in reducing blood pressure and triglyceride levels. Rosuvastatin is a lipid-lowering agent that lowers LDL (low-density lipoprotein) and triglycerides, while lowering HDL (high-density lipoprotein) cholesterol. Therefore, the use of statins can be considered safe and effective in patients with hyperlipidemia. It is important to note that there may be some adverse effects of rosuvastatin in some patients, such as increased heart attack, stroke, or liver damage, which may be more severe than the effects of statins.

The most common side effects of statins are gastrointestinal issues, including nausea, diarrhea, and abdominal discomfort. Rosuvastatin is contraindicated in patients with a history of peptic ulceration or perforation of the stomach or intestines. It is contraindicated in patients taking statins with an increased risk of myocardial infarction, stroke, or cardiovascular death due to myocardial infarction in patients with a history of cardiovascular disease.

Phenotyping of Rosuvastatin-Resistant Patients

The use of rosuvastatin as a lipid lowering agent can cause serious adverse effects, including cardiovascular events. This is because rosuvastatin is believed to increase the activity of certain enzymes in the body, resulting in decreased sensitivity to these enzymes. Therefore, the use of rosuvastatin in patients with hyperlipidemia should be considered for those patients who develop cardiovascular adverse reactions. The use of rosuvastatin in patients with an increased risk of myocardial infarction should also be considered for those patients who develop cardiovascular adverse reactions.

The use of rosuvastatin in patients with hyperlipidemia should be considered for those patients who are at a risk of cardiovascular events. Patients taking rosuvastatin should be carefully monitored during treatment to detect any abnormal laboratory values and evaluate the clinical benefit of rosuvastatin in these patients.

Prevention of Heart Attack and Stroke

The use of statins, such as rosuvastatin, in patients with hyperlipidemia is thought to be associated with an increased risk of developing cardiovascular disease. This risk may be increased by reducing the intake of dietary fats, such as cholesterol and triglycerides, and by reducing the use of statins. Therefore, it is important to prevent the occurrence of cardiovascular events in patients taking statins while taking rosuvastatin.

It is also important to note that the risk of cardiovascular events seen in patients taking statins may be reduced in some patients, such as those who were already at a high risk of cardiovascular disease, as well as in those who were not on statins as a result of taking statins. It is recommended to take rosuvastatin daily for a minimum of 2 years before evaluating the cardiovascular risk of patients taking statins.

Rosuvastatin should be used as a lipid lowering agent in patients with hyperlipidemia.